A general metal-free route towards the synthesis of 1,2,3-triazoles from readily available primary amines and ketones.
نویسندگان
چکیده
An unprecedented approach that enables the direct and selective preparation of 1,5-disubstituted 1,2,3-triazoles from abundantly available building blocks such as primary amines, enolizable ketones and 4-nitrophenyl azide as a renewable source of dinitrogen via an organocascade process has been developed. Furthermore, this efficient methodology also enables the synthesis of fully functionalized and fused N-substituted heterocycles.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 52 14 شماره
صفحات -
تاریخ انتشار 2016